cDNA Clone RNF111

• Synonyms: ARK
• Plasmid: pSC-B-RNF111 tv3 N9K Xho Not
• Parent Plasmid: pSC-B
• Genbank: NM_017610.6
• Species: Human

Sequence of Insert

CTCGAGATGTCTCAATGGACTCCTGAATATAAGGAGCTCTACACCTTAAAAGTGGATATGAAGAGTGAGATTCCTTCTGATGCACCAAAGACACAGGAGAGTCTGAAAGGGATCCTTTTGCATCCAGAGCCCATTGGGGCAGCCAAAAGTTTTCCTGCAGGAGTTGAGATGATTAATAGTAAAGTGGGGAATGAATTCTCTCACCTGTGTGATGATTCTCAAAAGCAAGAGAAGGAAATGAATGGTAACCAGCAAGAACAAGAAAAAAGTCTCGTTGTGAGGAAAAAACGCAAAAGCCAGCAGGCTGGCCCTTCGTATGTGCAGAATTGTGTTAAAGAAAACCAGGGAATATTAGGACTGAGGCAACACCTAGGGACACCAAGTGATGAAGATAATGATTCCTCTTTTAGTGATTGTCTTTCTTCTCCTTCATCTAGTCTGCATTTTGGGGATTCTGATACTGTGACTTCAGATGAGGATAAAGAAGTCTCTGTAAGACATTCCCAGACCATTTTGAATGCTAAAAGTAGAAGCCATAGTGCACGGTCTCATAAGTGGCCTCGGACTGAGACAGAATCTGTATCGGGATTGTTAATGAAAAGACCCTGTTTACATGGCAGTTCGTTACGGAGACTTCCATGCAGAAAGAGATTTGTAAAAAATAATTCCTCACAGAGGACACAGAAACAAAAAGAGAGGATATTAATGCAGAGGAAGAAACGAGAAGTGTTAGCTCGAAGAAAATATGCCTTGCTACCTAGTTCTAGTAGTTCCAGTGAGAATGACCTCAGCAGTGAATCCTCTTCTAGCTCATCAACTGAAGGAGAAGAAGATTTGTTTGTTTCTGCCAGTGAAAACCACCAAAACAATCCAGCTGTTCCCTCAGGAAGTATTGATGAAGATGTTGTGGTGATAGAAGCTTCCTCCACTCCCCAGGTTACTGCCAATGAAGAAATTAATGTTACCTCAACTGACAGTGAAGTGGAGATTGTAACAGTTGGAGAAAGCTATCGGTCTCGTTCAACCCTTGGACACTCCAGATCTCATTGGAGCCAGGGTTCCAGTTCTCATGCAAGTCGGCCACAGGAGCCACGGAACCGCAGTAGGATTTCTACTGTTATACAGCCCTTGAGGCAGAATGCAGCAGAAGTTGTGGACCTTACCGTTGATGAAGATGAACCTACTGTAGTACCAACCACTTCTGCAAGAATGGAATCACAAGCTACTAGCGCTTCCATTAACAATTCAAATCCATCTACCTCTGAGCAGGCCTCTGATACTGCTTCAGCTGTCACCAGTAGCCAACCTTCCACAGTGTCAGAGACTTCAGCTACTCTTACAAGCAATAGTACCACTGGCACTTCTATAGGAGATGACTCAAGGAGAACTACATCTAGTGCTGTAACGGAAACTGGCCCTCCTGCAATGCCAAGGTTACCTTCCTGCTGTCCCCAGCACTCACCATGTGGAGGGTCGTCACAGAACCACCATGCATTAGGACATCCTCATACAAGTTGCTTTCAGCAGCATGGTCACCATTTTCAACATCATCACCACCACCACCATACTCCCCACCCAGCTGTCCCAGTTTCTCCTTCCTTTAGTGATCCTGCTTGCCCTGTGGAAAGACCTCCACAAGTACAAGCACCTTGTGGAGCAAATAGTAGTTCTGGTACCAGCTATCATGAACAGGCATTGCCAGTGGACCTGAGCAACAGTGGTATCAGAAGTCATGGAAGTGGCAGTTTTCATGGAGCATCTGCATTTGACCCCTGCTGCCCTGTTTCTTCCTCCCGAGCTGCAATCTTTGGCCATCAGGCCGCTGCTGCTGCCCCAAGTCAACCTTTATCATCAATAGATGGCTATGGATCAAGCATGGTTGCGCAGCCCCAGCCCCAGCCCCCTCCACAGCCCTCTCTCTCATCATGTCGACATTACATGCCACCCCCTTATGCCTCTTTGACAAGGCCACTTCATCATCAAGCTTCTGCCTGCCCGCATTCTCATGGAAACCCCCCTCCTCAGACTCAGCCTCCGCCTCAAGTGGATTATGTTATTCCTCATCCTGTACATGCTTTCCATTCTCAAATATCTTCTCATGCAACATCTCATCCTGTGGCACCCCCACCACCAACTCACTTAGCCAGTACAGCTGCACCAATCCCTCAGCATCTTCCTCCTACACACCAGCCAATTTCGCACCATATTCCAGCCACAGCACCTCCAGCACAGAGACTGCATCCTCATGAAGTGATGCAGAGGATGGAAGTTCAAAGGAGGAGGATGATGCAGCATCCAACGCGGGCACATGAACGCCCCCCACCCCATCCACATAGGATGCACCCAAACTATGGTCATGGGCATCATATTCATGTGCCTCAGACTATGTCCTCACATCCTCGACAGGCTCCAGAGAGGTCTGCCTGGGAACTGGGAATTGAAGCTGGAGTGACTGCAGCTACTTATACACCTGGTGCATTGCATCCTCACTTGGCCCATTATCACGCACCTCCTCGACTTCATCACTTACAATTAGGAGCTCTTCCTTTAATGGTTCCTGATATGGCAGGCTATCCTCACATCCGTTACATTTCATCAGGATTGGATGGAACATCATTCAGAGGTCCTTTCAGGGGCAATTTTGAGGAACTGATTCATTTGGAAGAAAGATTAGGCAATGTCAATCGTGGAGCATCCCAGGGGACAATTGAAAGATGTACATATCCACATAAATACAAAAAGAGGAAACTGCACTGCAAACAAGATGGGGAAGAAGGGACTGAGGAAGACACAGAGGAAAAATGTACTATCTGTTTGTCTATTTTAGAGGAAGGTGAAGATGTGAGACGTCTTCCATGTATGCACCTTTTCCACCAAGTGTGTGTTGACCAATGGTTGATTACCAATAAGAAGTGCCCCATATGCAGAGTGGACATTGAGGCCCAGCTGCCAAGTGAAAGTTGAGCGGCCGC

Amino Acid Sequence

MSQWTPEYKELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVERPPQVQAPCGANSSSGTSYHEQALPVDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVNRGASQGTIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES*

• Antibiotic: Amp
• DU Number: DU37960
• Unit Source: Protein Phosphorylation and Ubiquitylation Unit
• Location: PPU
• MTA: Dundee
• Notes: C>G 27 bp leading to N9K variation, This is shown to be deleterious (Ensembl) and will require repair. This clone is identical to variant one except it is missing Q563.Silent change A>G 444 bp.