cDNA Clone PHLPP2

• Synonyms: PH domain and leucine rich repeat protein phosphatase 2, PPM3B, PHLPPL
• Plasmid: pSc-B-PHLPP2
• Parent Plasmid: pSC-B
• Genbank: Gene 23035 NM_015020.3 → NP_055835.2
• Species: Human

Sequence of Insert

gctagcATGAAACGCAATGGGAGCAGAAATTGTTTGAATAGGAGAAGTAG
GTTTGGTTCTCGAGAAAGAGACTGGCTAAGAGAAGATGTAAAGAGAGGCT
GTGTTTACCTTTATGGAGCAGACACTACCACTGCCACTACAACCACCACC
ACCTCCTCTTCCTCTTCCTCCTCCTCCTCTTCCTCTGACTTACATCTCGT
CCTTTGCACTGTAGAGACACCAGCATCAGAAATATGTGCTGGAGAGGGAA
GAGAAAGTCTTTATTTACAGCTTCATGGAGACCTGGTCAGGAGACTGGAA
CCTACTGAACGACCTCTTCAGATCGTTTATGATTACTTATCCAGGCTGGG
ATTTGATGATCCTGTGCGCATACAGGAGGAGGCTACAAATCCTGACCTCG
GCTGTATGATTCGATTTTATGGTGAAAAACCATGCCACATGGATCGTTTG
GATCGAATCCTATTGTCTGGCATCTATAATGTACGCAAGGGAAAGACCCA
GCTGCATAAGTGGGCTGAGCGCCTAGTTGTCCTCTGTGGTACCTGCCTTA
TCGTTTCCTCAGTGAAGGATTGTCAAACTGGAAAGATGCACATTTTGCCT
CTGGTTGGTGGAAAGATAGAAGAAGTGAAGCGACGGCAATACTCCCTTGC
TTTCAGCTCAGCAGGAGCCCAAGCTCAGACCTATCATGTCAGCTTCGAGA
CTTTGGCCGAGTACCAGCGATGGCAACGGCAAGCATCCAAGGTGGTGTCC
CAGCGAATCAGTACCGTGGATCTCTCGTGTTACAGCCTCGAGGAGGTTCC
TGAGCATCTCTTCTATAGTCAAGATATTACCTACCTCAACTTGCGACACA
ACTTCATGCAGTTAGAAAGACCCGGAGGCCTCGATACACTCTACAAATTT
TCTCAACTGAAGGGCCTGAACTTGTCCCATAATAAACTTGGGTTGTTTCC
TATATTGTTATGCGAGATCTCTACCCTGACTGAGCTCAACCTTTCCTGTA
ATGGATTTCATGACCTACCAAGTCAAATTGGCAATCTGCTAAATCTTCAA
ACCCTCTGTCTTGATGGCAACTTTCTGACTACTTTACCTGAAGAATTGGG
AAATCTACAACAGCTTTCCTCCTTGGGAATTTCCTTCAACAACTTTAGTC
AAATTCCTGAGGTTTATGAGAAACTCACTATGTTAGATAGAGTGGTTATG
GCAGGAAATTGCCTGGAAGTCCTGAACTTAGGGGTGCTGAATAGGATGAA
CCATATCAAGCATGTGGATTTAAGGATGAACCATTTGAAAACCATGGTTA
TTGAAAATCTGGAGGGAAATAAACACATCACCCACGTGGATCTGCGGGAC
AACCGACTGACTGACTTGGATCTTAGCTCCTTATGCAGCTTGGAACAGCT
GCACTGTGGGCGGAATCAGCTGAGGGAGCTAACACTCAGTGGCTTTTCCC
TTCGGACCCTCTATGCCAGTTCCAACAGGCTGACAGCAGTGAACGTCTAT
CCAGTACCCAGCCTGCTCACTTTCTTGGATCTCTCCCGAAACCTGCTAGA
GTGTGTCCCTGACTGGGCCTGTGAAGCAAAGAAGATAGAAGTATTAGATG
TGAGCTATAATCTTCTCACAGAGGTTCCCGTGAGAATTCTGAGTAGCTTG
AGTCTTAGAAAACTGATGCTGGGACACAATCATGTGCAAAACCTTCCAAC
ACTGGTAGAGCACATCCCCCTCGAGGTGCTGGATCTTCAGCATAATGCAC
TCACGAGGCTGCCAGACACCCTCTTCTCCAAGGCCTTAAATCTCAGATAC
TTGAATGCATCTGCAAATAGTCTGGAGTCTTTACCATCCGCCTGCACTGG
AGAGGAGAGTTTGAGTATGCTGCAGCTGCTTTATCTGACCAACAATCTCC
TGACGGATCAGTGCATACCTGTCCTGGTAGGGCACCTGCACCTGCGAATC
TTGCACCTTGCAAACAATCAGTTACAGACCTTTCCTGCAAGCAAACTAAA
TAAATTGGAGCAATTGGAGGAACTGAACCTAAGTGGCAACAAGCTTAAAA
CCATTCCCACAACCATAGCAAACTGTAAAAGGCTGCACACCCTTGTTGCA
CACTCCAACAACATCAGCATTTTCCCAGAAATACTGCAGTTGCCTCAGAT
CCAGTTTGTAGACCTAAGTTGCAACGACTTGACAGAAATCCTGATTCCAG
AGGCTTTGCCTGCTACATTACAAGACCTTGACCTGACTGGAAATACAAAT
CTGGTTCTGGAACACAAGACACTGGACATATTTAGCCATATCACAACCCT
GAAAATTGATCAGAAACCTTTGCCAACCACAGATTCTACAGTTACGTCAA
CCTTCTGGAGCCATGGACTGGCTGAGATGGCAGGGCAGAGAAATAAGCTG
TGTGTCTCAGCACTTGCTATGGATAGCTTTGCAGAGGGGGTGGGAGCTGT
GTATGGCATGTTTGATGGAGACCGAAATGAGGAGCTCCCGCGCCTGCTGC
AGTGTACGATGGCAGATGTGCTTTTAGAAGAGGTACAGCAGTCAACTAAT
GACACAGTTTTCATGGCTAACACCTTCTTGGTATCTCACAGGAAATTAGG
AATGGCTGGCCAGAAGTTGGGCTCCTCCGCTCTCCTGTGCTACATCCGCC
CTGACACTGCCGATCCAGCAAGTAGCTTTAGCTTGACTGTAGCCAATGTT
GGCACGTGCCAAGCAGTCCTGTGCCGAGGTGGGAAGCCAGTGCCCCTCTC
TAAAGTCTTCAGCCTGGAGCAGGACCCAGAGGAGGCTCAAAGGGTGAAGG
ACCAAAAAGCCATCATCACAGAGGACAACAAAGTGAATGGGGTAACCTGC
TGTACCCGGATGCTGGGCTGTACATACCTCTACCCTTGGATCCTCCCCAA
GCCCCACATATCTTCCACTCCGCTGACCATTCAAGATGAGTTGCTGATTC
TGGGAAACAAAGCATTGTGGGAACACTTGTCCTACACAGAAGCTGTCAAT
GCTGTACGTCACGTACAAGACCCATTAGCAGCTGCTAAGAAGCTGTGCAC
ATTAGCGCAGAGCTATGGCTGTCAGGACAATGTAGGGGCGATGGTAGTTT
ATTTGAATATTGGTGAGGAAGGCTGCACTTGTGAAATGAATGGGCTCACC
CTCCCAGGTCCTGTGGGATTTGCTTCAACCACCACTATCAAGGATGCCCC
TAAGCCAGCCACTCCATCCTCTAGCAGTGGGATTGCCTCTGAGTTCAGCA
GTGAGATGTCCACCTCAGAGGTGAGCAGTGAAGTGGGGTCCACTGCTTCT
GATGAGCATAATGCTGGGGGCCTGGACACTGCCTTGCTTCCGAGGCCAGA
GCGGCGCTGCAGCCTCCACCCAACACCCACCTCTGGGCTGTTTCAGCGCC
AGCCTTCTTCTGCTACCTTCTCCAGTAACCAGTCTGACAACGGCCTGGAC
AGTGATGATGACCAGCCCGTTGAGGGGGTCATAACCAATGGCAGCAAGGT
AGAGGTGGAAGTAGACATCCACTGCTGCAGGGGGAGGGATCTGGAGAACT
CACCCCCTCTCATAGAGAGTTCTCCTACCCTGTGTTCTGAGGAACATGCT
AGAGGGTCGTGTTTTGGGATCCGAAGACAGAACAGTGTGAATAGTGGCAT
GCTCCTGCCAATGAGCAAGGACAGGATGGAGTTACAGAAGTCTCCCTCCA
CCTCCTGCCTCTATGGGAAGAAACTCTCCAATGGCTCTATTGTGCCCCTA
GAGGACAGCCTGAACCTCATTGAAGTGGCCACAGAAGTGCCCAAGAGGAA
AACTGGCTATTTTGCTGCCCCCACTCAGATGGAACCAGAGGACCAGTTTG
TTGTGCCTCATGACCTGGAAGAAGAAGTGAAGGAACAAATGAAACAGCAC
CAGGACAGCCGGCTCGAGCCTGAGCCCCATGAAGAGGATCGGACCGAGCC
CCCGGAGGAGTTCGACACAGCACTATGAgcggccgc

Amino Acid Sequence

MKRNGSRNCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTTTS
SSSSSSSSSSDLHLVLCTVETPASEICAGEGRESLYLQLHGDLVRRLEPT
ERPLQIVYDYLSRLGFDDPVRIQEEATNPDLGCMIRFYGEKPCHMDRLDR
ILLSGIYNVRKGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILPLV
GGKIEEVKRRQYSLAFSSAGAQAQTYHVSFETLAEYQRWQRQASKVVSQR
ISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQ
LKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTL
CLDGNFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAG
NCLEVLNLGVLNRMNHIKHVDLRMNHLKTMVIENLEGNKHITHVDLRDNR
LTDLDLSSLCSLEQLHCGRNQLRELTLSGFSLRTLYASSNRLTAVNVYPV
PSLLTFLDLSRNLLECVPDWACEAKKIEVLDVSYNLLTEVPVRILSSLSL
RKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLN
ASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLHLRILH
LANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHS
NNISIFPEILQLPQIQFVDLSCNDLTEILIPEALPATLQDLDLTGNTNLV
LEHKTLDIFSHITTLKIDQKPLPTTDSTVTSTFWSHGLAEMAGQRNKLCV
SALAMDSFAEGVGAVYGMFDGDRNEELPRLLQCTMADVLLEEVQQSTNDT
VFMANTFLVSHRKLGMAGQKLGSSALLCYIRPDTADPASSFSLTVANVGT
CQAVLCRGGKPVPLSKVFSLEQDPEEAQRVKDQKAIITEDNKVNGVTCCT
RMLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAV
RHVQDPLAAAKKLCTLAQSYGCQDNVGAMVVYLNIGEEGCTCEMNGLTLP
GPVGFASTTTIKDAPKPATPSSSSGIASEFSSEMSTSEVSSEVGSTASDE
HNAGGLDTALLPRPERRCSLHPTPTSGLFQRQPSSATFSSNQSDNGLDSD
DDQPVEGVITNGSKVEVEVDIHCCRGRDLENSPPLIESSPTLCSEEHARG
SCFGIRRQNSVNSGMLLPMSKDRMELQKSPSTSCLYGKKLSNGSIVPLED
SLNLIEVATEVPKRKTGYFAAPTQMEPEDQFVVPHDLEEEVKEQMKQHQD
SRLEPEPHEEDRTEPPEEFDTAL*

• Vector Type: Other
• Antibiotic: Amp; Kan
• DU Number: DU65260
• Unit Source: Protein Phosphorylation and Ubiquitylation Unit
• Location: PPU
• MTA: Dundee
• Notes: isoform 1
• Low Temp: No