Human Recombinant Protein - PI3 Kinase alpha H1047R (2 - 1068), p85 (1 - 724)

Name: PI3 Kinase alpha H1047R (2 - 1068), p85 (1 - 724)
Price per aliquot (100µg): £125.00
Synonyms:
PIK3C2A, PIK3R1
Species:
Human
Catalog Number (DU Number):
DU12759
Accession:
U79143, NM_181523
Expression:
baculovirus
Tag and Terminus:
N-Term
6His
Uncleaved
Purification Method:
Nickel Agarose
Calculated molecular mass:
Mono-Isotopic Mass: 125, 125.99 daltons [PI3 kinase alpha] and 83,546.54 daltons [p85]
Average Mass: 125, 044.42 daltons [PI3 kinase alpha] and 83,589.39 daltons [p85]
Purity:
>80 %
Storage Buffer:
50 mM Hepes/NaOH pH 7.0, 150 mM NaCl, 5 mM DTT, 20 % glycerol
Storage Temperature:
-70 deg C
Theoretical PI:
7.05 for PI3 kinase alpha and 5.84 for p85
Native Sequence:
Amino acids P2 – N1068 (end residue) of human PI3 kinase alpha. Residue P8 of the fusion protein is equivalent to P2 of the native enzyme. The enzyme has an H1047R mutation found in many types of cancers. Residue H1047 is equivalent to R1053 The His(6) tag is located at residues 2 - 7. Amino acids M1 – R724 (end residue) of human p85.

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