cDNA Clone HMMR

• Synonyms: hyaluronan mediated motility receptor isoform c
• Plasmid: pcDNA5D FRT/TO mCherry-HMMR isoform c
• Parent Plasmid: pcDNA5D FRT/TO mCherry
• Expressed: mCherry-HMMR isoform c
• Genbank: NM_012485.2 → NP_036617.2
• Tag: mCherry
• Species: Human

Sequence of Insert

ggtaccATGTCCTTTCCTAAGGCGCCCTTGAAACGATTCAATGACCCTTC
TGGTTGTGCACCATCTCCAGGTGCTTATGATGTTAAAACTTTAGAAGTAT
TGAAAGGACCAGTATCCTTTCAGAAATCACAAAGATTTAAACAACAAAAA
GAATCTAAACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTC
AGCTAGAAAAGTTAAGTCTTCGGAATCAAAGATTCGTGTTCTTCTACAGG
AACGTGGTGCCCAGGACAGGCGGATCCAGGATCTGGAAACTGAGTTGGAA
AAGATGGAAGCAAGGCTAAATGCTGCACTAAGGGAAAAAACATCTCTCTC
TGCAAATAATGCTACACTGGAAAAACAACTTATTGAATTGACCAGGACTA
ATGAACTACTAAAATCTAAGTTTTCTGAAAATGGTAACCAGAAGAATTTG
AGAATTCTAAGCTTGGAGTTGATGAAACTTAGAAACAAAAGAGAAACAAA
GATGAGGGGTATGATGGCTAAGCAAGAAGGCATGGAGATGAAGCTGCAGG
TCACCCAAAGGAGTCTCGAAGAGTCTCAAGGGAAAATAGCCCAACTGGAG
GGAAAACTTGTTTCAATAGAGAAAGAAAAGATTGATGAAAAATCTGAAAC
AGAAAAACTCTTGGAATACATCGAAGAAATTAGTTGTGCTTCAGATCAAG
TGGAAAAATACAAGCTAGATATTGCCCAGTTAGAAGAAAATTTGAAAGAG
AAGAATGATGAAATTTTAAGCCTTAAGCAGTCTCTTGAGGAGAATATTGT
TATATTATCTAAACAAGTAGAAGATCTAAATGTGAAATGTCAGCTGCTTG
AAAAAGAAAAAGAAGACCATGTCAACAGGAATAGAGAACACAACGAAAAT
CTAAATGCAGAGATGCAAAACTTAAAACAGAAGTTTATTCTTGAACAACA
GGAACGTGAAAAGCTTCAACAAAAAGAATTACAAATTGATTCACTTCTGC
AACAAGAGAAAGAATTATCTTCGAGTCTTCATCAGAAGCTCTGTTCTTTT
CAAGAGGAAATGGTTAAAGAGAAGAATCTGTTTGAGGAAGAATTAAAGCA
AACACTGGATGAGCTTGATAAATTACAGCAAAAGGAGGAACAAGCTGAAA
GGCTGGTCAAGCAATTGGAAGAGGAAGCAAAATCTAGAGCTGAAGAATTA
AAACTCCTAGAAGAAAAGCTGAAAGGGAAGGAGGCTGAACTGGAGAAAAG
TAGTGCTGCTCATACCCAGGCCACCCTGCTTTTGCAGGAAAAGTATGACA
GTATGGTGCAAAGCCTTGAAGATGTTACTGCTCAATTTGAAAGCTATAAA
GCGTTAACAGCCAGTGAGATAGAAGATCTTAAaCTGGAGAACTCATCATT
ACAGGAAAAAGtGGCCAAGGCTGGGAAAAATGCAGAGGATGTTCAGCATC
AGATTTTGGCAACTGAGAGCTCAAATCAAGAATATGTAAGGATGCTTCTA
GATCTGCAGACCAAGTCAGCACTAAAGGAAACAGAAATTAAAGAAATCAC
AGTTTCTTTTCTTCAAAAAATAACTGATTTGCAGAACCAACTCAAGCAAC
AGGAGGAAGACTTTAGAAAACAGCTGGAAGATGAAGAAGGAAGAAAAGCT
GAAAAAGAAAATACAACAGCAGAATTAACTGAAGAAATTAACAAGTGGCG
TCTCCTCTATGAAGAACTATATAATAAAACAAAACCTTTTCAGCTACAAC
TAGATGCTTTTGAAGTAGAAAAACAGGCATTGTTGAATGAACATGGTGCA
GCTCAGGAACAGCTAAATAAAATAAGAGATTCATATGCTAAATTATTGGG
TCATCAGAATTTGAAACAAAAAATCAAGCATGTTGTGAAGTTGAAAGATG
AAAATAGCCAACTCAAATCGGAAGTATCAAAACTCCGCTGTCAGCTTGCT
AAAAAAAAACAAAGTGAGACAAAACTTCAAGAGGAATTGAATAAAGTTCT
AGGTATCAAACACTTTGATCCTTCAAAGGCTTTTCATCATGAAAGTAAAG
AAAATTTTGCCCTGAAGACCCCATTAAAAGAAGGCAATACAAACTGTTAC
CGAGCTCCTATGGAGTGTCAAGAATCATGGAAGTAAgcggccgc

Amino Acid Sequence

MVSKGEEDNMAIIKEFMRFKVHMEGSVNGHEFEIEGEGEGRPYEGTQTAK
LKVTKGGPLPFAWDILSPQFMYGSKAYVKHPADIPDYLKLSFPEGFKWER
VMNFEDGGVVTVTQDSSLQDGEFIYKVKLRGTNFPSDGPVMQKKTMGWEA
SSERMYPEDGALKGEIKQRLKLKDGGHYDAEVKTTYKAKKPVQLPGAYNV
NIKLDITSHNEDYTIVEQYERAEGRHSTGGMDELYKSGLGSSRKGTMSFP
KAPLKRFNDPSGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNL
NVDKDTTLPASARKVKSSESKIRVLLQERGAQDRRIQDLETELEKMEARL
NAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLE
LMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSI
EKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEIL
SLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQ
NLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVK
EKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEK
LKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASE
IEDLKLENSSLQEKVAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKS
ALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTT
AELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLN
KIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKKKQSE
TKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYRAPMEC
QESWK*

• Vector Type: Mammalian
• Antibiotic: Amp
• DU Number: DU28340
• Unit Source: Protein Phosphorylation and Ubiquitylation Unit
• Location: PPU
• MTA: Dundee
• Notes: This variant (3) is missing an in-frame coding exon compared to transcript variant 1, resulting in an isoform (c) which lacks an internal 16 aa segment (Lys76-Glu91) compared to isoform a. Silent mutation at K459. Listed polymorphisms Ala469>Val (listed as SNP for aa485 of isoform a) and Val353>Ala (listed as SNP for aa369 of isoform a)